Background: Transjugular intrahepatic portosystemic shunt (TIPS) has been shown as an effective treatment of portal hypertension-related complications with beneficial effects on morbidity and mortality in selected patients. However, severe complications, such as post-TIPS HE and acute on chronic hepatic failure demand for optimal selection of candidates. Of the various risk-stratification tools that have been published, the Model of End-Stage Liver Disease (MELD) is the so far best validated model to predict post-TIPS mortality. Methods: Utilizing data from 158 cases of TIPS placement between 01/2004 and 12/2017 at the University Hospital Graz, we aimed to develop a mortality-predicting tool with beneficial features compared to MELD. Results: 144 patients were included in the analysis. Univariate and multivariate analyses of factors predicting mortality within 90 days were performed and a score integrating urea, INR and bilirubin was developed. Modified TIPS-Score (MOTS) ranges from 0-3 points: INR >1.6, urea >71 mg/dl and bilirubin >2.2 mg/dl imply plus one point each. 90-day mortality rates were 4%, 13%, 50% and 75% in patients with MOTS 0 points (n=50), 1 point (n=40), 2 points (n=12) and 3 points (n=8), respectively (p
A novel score to predict mortality after transjugular intrahepatic portosystemic shunt (TIPS)
Fürschuß, L. S. (Author). 2020
Student thesis: Diploma thesis