Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.

RA Maki; Michael Holzer; K Motamedchaboki; Ernst Malle; E Masliah; Gunther Marsche; WF Reynolds

doi:10.1016/j.freeradbiomed.2019.05.033

Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.

RA Maki
, Michael Holzer
, K Motamedchaboki
, Ernst Malle
, E Masliah
, Gunther Marsche
, WF Reynolds

Research output: Contribution to journal › Research article

46 Citations (Web of Science)

Original language	English
Journal	Free Radical Biology and Medicine
DOIs	https://doi.org/10.1016/j.freeradbiomed.2019.05.033
Publication status	Published - 2019

Branches of science

104 Chemistry
301 Medical-Theoretical Sciences, Pharmacy
305 Other Human Medicine, Health Sciences

DOI

10.1016/j.freeradbiomed.2019.05.033

Links

Cite this

Maki, RA., Holzer, M., Motamedchaboki, K., Malle, E., Masliah, E., Marsche, G., & Reynolds, WF. (2019). Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2019.05.033

@article{3e0d31cb08d74defb39902180ce4067e,

title = "Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.",

author = "RA Maki and Michael Holzer and K Motamedchaboki and Ernst Malle and E Masliah and Gunther Marsche and WF Reynolds",

year = "2019",

doi = "10.1016/j.freeradbiomed.2019.05.033",

language = "English",

journal = "Free Radical Biology and Medicine",

issn = "0891-5849",

publisher = "Elsevier Inc.",

}

Maki, RA, Holzer, M, Motamedchaboki, K, Malle, E, Masliah, E, Marsche, G & Reynolds, WF 2019, 'Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.', Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2019.05.033

Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment. / Maki, RA; Holzer, Michael; Motamedchaboki, K et al.
In: Free Radical Biology and Medicine, 2019.

Research output: Contribution to journal › Research article

TY - JOUR

T1 - Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.

AU - Maki, RA

AU - Holzer, Michael

AU - Motamedchaboki, K

AU - Malle, Ernst

AU - Masliah, E

AU - Marsche, Gunther

AU - Reynolds, WF

PY - 2019

Y1 - 2019

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000483920100011

UR - https://pubmed.ncbi.nlm.nih.gov/31175983

UR - https://pmc.ncbi.nlm.nih.gov/articles/PMC6774439

U2 - 10.1016/j.freeradbiomed.2019.05.033

DO - 10.1016/j.freeradbiomed.2019.05.033

M3 - Research article

C2 - 31175983

SN - 0891-5849

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

ER -

Maki RA, Holzer M, Motamedchaboki K, Malle E, Masliah E, Marsche G et al. Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment. Free Radical Biology and Medicine. 2019. doi: 10.1016/j.freeradbiomed.2019.05.033