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Most recent collaborations and top research areas
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A novel cytokine based therapeutic strategy for treating acute myeloid leukemia
Dutta, S. (Principal investigator)
1/04/25 → 31/03/27
Project: Research funding
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Tp53 in AML: In vivo competition of AML cells harboring different TP53 aberrations
Dutta, S. (Principal investigator)
1/06/25 → 1/06/26
Project: Research funding
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Identifying novel targets to combat aberrant TP53 mediated therapeutic resistance in acute myeloid leukemia using CRISPRko screens
Dutta, S. (Principal investigator)
1/02/24 → 31/07/26
Project: Research funding
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TP53 bei AML: Significance of small, TP53 mutated clones in acute myeloid leukemia
Sill, H. (Principal investigator), Dutta, S. (Co-investigator), Lind, K. (Co-investigator) & Zöscher, F. (Co-investigator)
2/01/19 → 1/07/23
Project: Research funding
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TP53 in AML: Somatic TP53 mutations in the pathogenesis of acute myeloid leukemia
Sill, H. (Principal investigator), Rezania, S. (Co-investigator), Dutta, S. (Co-investigator), Lal, R. (Co-investigator), Müller, M. (Co-investigator), Lind, K. (Co-investigator), Lyssy, F. (Co-investigator), Zöscher, F. (Co-investigator) & Schulz, E. (Co-investigator)
1/09/14 → 31/12/21
Project: Research funding
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Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
Höckendorf, U., Dutta, S. (First author), Kloos, A., Runtsch, M., Zötsch, C., Vosberg, S., Wang, Y., Kienreich, S., Flasch, B., Jäger, V., Stanzer, S., Prein, S., Odinius, T., Wagner, C., Buschhorn, L., Dill, V., Perfler, B., Haferlach, T., Döhner, K. & Götze, K. & 15 others, , 26 Nov 2025, In: Science Translational Medicine. 17, 826, p. eadu3313 15 p., eadu3313.Research output: Contribution to journal › Research article
1 Citation (Web of Science) -
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia.
Edtmayer, S., Witalisz-Siepracka, A., Zdársky, B., Heindl, K., Weiss, S., Eder, T., Dutta, S., Graichen, U., Klee, S., Sharif, O., Wieser, R., Győrffy, B., Poli, V., Casanova, E., Sill, H., Grebien, F. & Stoiber, D., 28 May 2024, In: Cell Death and Disease. 15, 5, p. 369 12 p., 369.Research output: Contribution to journal › Research article
6 Citations (Web of Science) -
Impact of Mono- and Bi-Allelic TP53 Aberrations on Transformation of Human HSPCs
Lind, K., Dutta, S., Cosenza, M., Langsenlehner, T., Folsselteder, J., Pabst, G., Schöll, W., Prokesch, A., Reinisch, A., Wölfler, A., Zebisch, A., Grebien, F., Korbel, J. & Sill, H., 2024, In: Blood. 144, 2 p.Research output: Contribution to journal › Conference abstract
1 Citation (Web of Science) -
Multi-drug algorithm to accurately predict best first-line treatments in newly-diagnosed acute myeloid leukemia (AML)
Cutillas, P., Borek, W., Christopher, J., Nobre, L., Campbell, A., Kelsall, J., Pedicona, F., Nawaz, N., Perkins, D., Cardoso, P., Arruda, A., Ambinder, A., Dutta, S., Gallipoli, P., Sill, H., Ghiaur, G., Minden, M., Williamson, A., Gribben, J. & Dokal, A., 1 Jun 2024, In: Journal of Clinical Oncology. 42, 16, 1 p.Research output: Contribution to journal › Conference abstract
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STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance.
Witalisz-Siepracka, A., Denk, C., Zdársky, B., Hofmann, L., Edtmayer, S., Harm, T., Weiss, S., Heindl, K., Hessenberger, M., Summer, S., Dutta, S., Casanova, E., Obermair, G., Győrffy, B., Putz, E., Sill, H. & Stoiber, D., 5 Jul 2024, In: Frontiers in Immunology. 15, p. 1374068 15 p., 1374068.Research output: Contribution to journal › Research article
8 Citations (Web of Science)
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STAT3β represses interferon signaling in acute myeloid leukemia contributing to favorable disease outcomes
Edtmayer, S. (Author), Witalisz-Siepracka, A. (Author), Zdársky, B. (Author), Weiss, S. (Author), Eder, T. (Author), Dutta, S. (Author), Wieser, R. (Author), Sill, H. (Author), Grebien, F. (Author) & Stoiber, D. (Author)
2024Activity: Talk, presentation or poster › Poster
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Multi-drug algorithm to accurately predict best first-line treatments in newly-diagnosed acute myeloid leukemia (AML)
Cutillas, P. (Author), Borek, W. (Author), Christopher, J. (Author), Nobre, L. (Author), Campbell, A. (Author), Kelsall, J. (Author), Pedicona, F. (Author), Nawaz, N. (Author), Perkins, D. (Author), Cardoso, P. (Author), Arruda, A. (Author), Ambinder, A. (Author), Dutta, S. (Author), Gallipoli, P. (Author), Sill, H. (Author), Ghiaur, G. (Author), Minden, M. (Author), Williamson, A. (Author), Gribben, J. (Author) & Dokal, A. (Author)
2024Activity: Talk, presentation or poster › Poster
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FREQUENT TRUNCATING MUTATIONS IN TET2 GENE AND A DISTINCT DNA METHYLATION SIGNATURE CHARACTERIZES ACUTE MYELOID LEUKEMIA WITH ISOLATED TRISOMY 4
Dutta, S. (Author), Kerbs, P. (Author), Rothenberg-Thurley, M. (Author), Ksienzyk, B. (Author), Krebs, S. (Author), Blum, H. (Author), Spiekermann, K. (Author), Metzeler, K. (Author), Herold, T. (Author), Dandachi, N. (Author), Vosberg, S. (Author) & Greif, P. (Author)
2023Activity: Talk, presentation or poster › Poster
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Modelling drug resistance conferred by mono- and bi-allelic TP53 aberrations using isogenic AML cell lines
Lyssy, F. (Author), Lind, K. (Author), Zöscher, F. (Author), Zebisch, A. (Author), Wölfler, A. (Author), Pabst, G. (Author), Foßelteder, J. (Author), Reinisch, A. (Author), Sill, H. (Author) & Dutta, S. (Author)
2023Activity: Talk, presentation or poster › Poster
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Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature
Dutta, S. (Author), Kerbs, P. (Author), Rothenberg-Thurley, M. (Author), Ksienzyk, B. (Author), Krebs, S. (Author), Blum, H. (Author), Spiekermann, K. (Author), Metzeler, K. (Author), Herold, T. (Author), Vosberg, S. (Author) & Greif, P. (Author)
2022Activity: Talk, presentation or poster › Poster