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Dive into the research topics where Oleksandra Tiapko is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 3 Active
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Establishing experimental models to study TRPC3 in neurodevelopmental disorders
Tiapko, O. (Principal investigator)
1/04/26 → 31/10/26
Project: Research funding
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Deciphering Alzheimer's: TRPC1 as a central player in protein unfolding and cholesterol biosynthesis
Tiapko, O. (Principal investigator)
1/03/24 → 31/12/26
Project: Research funding
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Resolving the open state enigma of TRPC3 by photopharmacology
Tiapko, O. (Principal investigator)
1/01/22 → 31/10/26
Project: Research funding
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Presenilin-1 controls glycolysis and identity of pancreatic beta cells
Koshenov, Z. (First author), Postic, S., Schoiswohl, G., van Amsterdam, S., Hois-Zelinka, V., Oflaz, F. E., Rost, R., Tiapko, O., Gottschalk, B., Hirtl, M., Bachkoenig, O. G., Koshenova, A., Erdogan, Y. C., Sagintayev, A., Krnjic, A., Pfabe, J. U., Sarikas, S., Hochreiter, B., Gindlhuber, J. & Schittmayer, M. & 10 others, , 1 Jul 2026, (E-pub ahead of print) In: Communications Biology.Research output: Contribution to journal › Research article
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Utilizing native nanodiscs to isolate active TRPC3 channels and expand structural analysis capabilities
Baron, J. (First author), Bauernhofer, L., Keller, S., Radner, F., Vargas, C., Leitinger, G., Bernauer, L., Emmerstorfer-Augustin, A., Wiedner, P., Durand, G., Soulié, M., Dorrer, V., Schittmayer, M., Birner-Gruenberger, R., Lichtenegger, M., Gsell, M., Groschner, K., Schindl, R. & Tiapko, O., 5 Aug 2025, In: Scientific Reports. 15, 1, p. 28562 15 p., 28562.Research output: Contribution to journal › Research article
2 Citations (Web of Science) -
Deciphering the mechanism of cholesterol sensing in TRPC3 through photopharmacology
Erkan Candag, H., Rochart, D., Tiapko, O., Sánchez Murcia, P. A., Glasnov, T., Stockner, T. & Groschner, K., 8 Feb 2024, In: Biophysical Journal. 123, 3, p. 393A-393A 1 p.Research output: Contribution to journal › Conference abstract
1 Citation (Web of Science) -
PIP2 modulates TRPC3 activity via TRP helix and S4-S5 linker.
Clarke, A., Skerjanz, J., Gsell, M., Wiedner, P., Erkan Candag, H., Groschner, K., Stockner, T. & Tiapko, O. (Last author), 18 Jun 2024, In: Nature Communications. 15, 1, p. 5220 13 p., 5220.Research output: Contribution to journal › Research article
11 Citations (Web of Science) -
TRPC1: The housekeeper of the hippocampus
Skerjanz, J. (First author), Bauernhofer, L., Lenk, K., Emmerstorfer-Augustin, A., Leitinger, G., Reichmann, F., Stockner, T., Groschner, K. & Tiapko, O. (Last author), Nov 2024, In: Cell Calcium. 123, p. 102933 9 p., 102933.Research output: Contribution to journal › Research article
9 Citations (Web of Science)
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Calcium-dependent cooperation between TRPC3 and SK3 channels yields profound hyperpolarization.
Tiapko, O. (Author), Derler, I. (Author) & Erkan-Candag, H. (Author)
2025Activity: Talk, presentation or poster › Poster
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TRPC1 in ER Calcium Dynamics: A Potential Leak Channel?.
Tiapko, O. (Author)
2025Activity: Talk, presentation or poster › Poster
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Exploring the role of TRPC1-IP3R cross-talk in the ER homeostasis
Tiapko, O. (Author)
2024Activity: Talk, presentation or poster › Poster
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Exploring the role of TRPC1-IP3R cross-talk in the ER homeostasis.
Tiapko, O. (Author)
2024Activity: Talk, presentation or poster › Poster
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Deciphering the mechanism of cholesterol sensing in TRPC3 through photopharmacology
Erkan Candag, H. (Author), Rochart, D. (Author), Tiapko, O. (Author), Sánchez Murcia, P. A. (Author), Glasnov, T. (Author), Stockner, T. (Author) & Groschner, K. (Author)
2024Activity: Talk, presentation or poster › Poster
Thesis
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Exploring lipid-mediated TRPC signaling by light
Tiapko, O. (Author), Graier, W. (Supervisor) & Groschner, K. (Supervisor), 2020Student thesis: Doctoral thesis