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Projects
- 2 Finished
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Mechanisms of Human Diabetic Cardiomyopathy
Byrne, N. (Principal investigator)
4/01/21 → 30/09/22
Project: Research funding
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SIRT4 and ischemia reperfusion: The role of SIRT4 in myocardial ischemia reperfusion
Bugger, H. M. (Principal investigator), Rathner, T. (Co-investigator), Byrne, N. (Co-investigator), Pfeil, K. (Co-investigator), Vosko, I. (Co-investigator) & Salon, A. (Co-investigator)
1/10/20 → 30/06/24
Project: Research funding
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Cardiomyocyte-Specific Deletion of Sirtuin 5 Accelerates the Development of Heart Failure Upon Dysregulating Purine Metabolism.
Byrne, N. (First author), Koentges, C., Pfeil, K., Lueg, J., Bakshi, S., Tarkhnishvili, A., Vosko, I., Gollmer, J., Birkle, L., Rathner, T., Birkle, S., Tang, S., Rau, C., Hoffmann, M., Odening, K., Barnes, S., Wilson, L., Holzer, S., Wallner, M. & von Lewinski, D. & 7 others, , Nov 2025, In: Acta Physiologica. 241, 11, p. e70120 14 p., e70120.Research output: Contribution to journal › Research article
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Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling
Byrne, N. (First author), Koentges, C., Khan, E., Pfeil, K., Sandulescu, R., Bakshi, S., Költgen, C., Vosko, I., Gollmer, J., Rathner, T., Rothf, G., Hoffmann, M., Odening, K., Orstmann, H., Potter, L., Boded, C., Wolf, D., Sourij, H., Ljubojevic-Holzera, S. & Wallnera, M. & 7 others, , Jun 2025, In: Journal of Molecular and Cellular Cardiology Plus. 12, p. 100299 14 p., 100299.Research output: Contribution to journal › Research article
5 Citations (Web of Science) -
Transient Inhibition of Translation Improves Cardiac Function After Ischemia/Reperfusion by Attenuating the Inflammatory Response.
Hofmann, C., Serafin, A., Schwerdt, O., Fischer, J., Sicklinger, F., Younesi, F., Byrne, N., Meyer, I., Malovrh, E., Sandmann, C., Jürgensen, L., Kamuf-Schenk, V., Stroh, C., Löwenthal, Z., Finke, D., Boileau, E., Beisaw, A., Bugger, H. M., Rettel, M. & Stein, F. & 5 others, , 15 Oct 2024, In: Circulation. 150, 16, p. 1248-1267 20 p.Research output: Contribution to journal › Research article
24 Citations (Web of Science) -
SIRT4 deficiency modifies fatty acid utilization in the normal and diabetic heart
Vosko, I., Holscher, M., Koentges, C., Tarkhnishvili, A., Byrne, N., Pfeil, K., Tang, S., Gollmer, J., Hoffmann, M., von Lewinski, D., Wallner, M., Bode, C., Zirlik, A. & Bugger, H. M., May 2023, In: Wiener Klinische Wochenschrift. 135, p. S454-S454 1 p.Research output: Contribution to journal › Conference abstract
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Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling
Byrne, N., Koentges, C., Khan, E., Pfeil, K., Sandulescu, R., Bakshi, S., Koltgen, C., Vosko, I., Gollmer, J., Hoffmann, M., Wolf, D., Holzer, S., Wallner, M., Rainer, P., Sedej, S., Scherr, D., von Lewinski, D., Wende, A., Zirlik, A. & Bugger, H. M., May 2023, In: Wiener Klinische Wochenschrift. 135, p. S398-S398 1 p.Research output: Contribution to journal › Conference abstract
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Loss of SIRT5 accelerates the development of pressure-overload induced heart failure upon dysregulating purine and pyrimidine metabolism
Byrne, N. (Speaker), Koentges, C. (Author), Pfeil, K. (Author), Lueg, J. (Author), Bakshi, S. (Author), Tarkhnishvili, A. (Author), Vosko, I. (Author), Gollmer, J. (Author), Birkle, L. (Author), Tang, S. (Author), Rau, C. (Author), Hoffman, M. (Author), Odenin, K. (Author), Barnes, S. (Author), Wilson, L. (Author), Holzer, S. (Author), Wallner, M. (Author), von Lewinski, D. (Author), Rainer, P. (Author), Sedej, S. (Author), Bode, C. (Author), Wende, A. (Author), Zirlik, A. (Author) & Bugger, H. M. (Author)
2024Activity: Talk, presentation or poster › Poster
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Loss of SIRT5 accelerates the development of pressure-overload induced heart failure upon dysregulating purine and pyrimidine metabolism
Byrne, N. (Speaker), Koentges, C. (Author), Pfeil, K. (Author), Lueg, J. (Author), Bakshi, S. (Author), Tarkhnishvili, A. (Author), Vosko, I. (Author), Gollmer, J. (Author), Birkle, L. (Author), Tang, S. (Author), Rau, C. (Author), Hoffman, M. (Author), Odenin, K. (Author), Barnes, S. (Author), Wilson, L. (Author), Holzer, S. (Author), Wallner, M. (Author), von Lewinski, D. (Author), Rainer, P. (Author), Sedej, S. (Author), Bode, C. (Author), Wende, A. (Author), Zirlik, A. (Author) & Bugger, H. M. (Author)
2024Activity: Talk, presentation or poster › Scientific talk or presentation › On site
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Nicotinamide Mononucleotide Supplementation Attenuates Atherosclerosis in Western Diet-Fed Ldlr-/- Mice
Byrne, N. (Speaker), Pfeil, K. (Author), Rathner, T. (Author), Cichocki, F. (Author), Költgen, C. (Author), Anto Michel, N. (Author), Zirlik, A. (Author) & Bugger, H. M. (Author)
2024Activity: Talk, presentation or poster › Scientific talk or presentation › On site
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Nicotinamide Mononucleotide Supplementation Attenuates Atherosclerosis in Western Diet-Fed Ldlr-/- Mice
Byrne, N. (Speaker), Pfeil, K. (Author), Rathner, T. (Author), Cichocki, F. (Author), Költgen, C. (Author), Anto Michel, N. (Author), Zirlik, A. (Author) & Bugger, H. M. (Author)
2024Activity: Talk, presentation or poster › Scientific talk or presentation › On site
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Cardiovascular Research (Journal)
Byrne, N. (Reviewer)
2024Activity: Peer-review and editorial work › Peer-review activitiy