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Dive into the research topics where Michael Dengler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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CDL: Dengler: Christian Doppler (CD) Laboratory for Activation of Immunogenic Cell Death in Lung Cancer
Dengler, M. (Principal investigator)
1/01/26 → 31/12/27
Project: Research funding
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SARAH: Search for combinational therapy to target clonal haematopoiesis in solid malignancies
Dengler, M. (Principal investigator)
1/10/25 → 30/09/28
Project: Research funding
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Identifying novel lung cancer drivers: Unravelling the functional role of genes affected by large copy number gains
Dengler, M. (Principal investigator)
1/10/24 → 31/12/26
Project: Research funding
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Using dual CRISPRko and CRISPRa screens to identify novel targets to overcome cancer drug resistance
Dengler, M. (Principal investigator), Flasch, B. (Co-investigator) & Balihodzic, A. (Co-investigator)
1/01/22 → 31/12/24
Project: Research funding
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Targeting the apoptotic pathway to overcome therapy resistance in lung cancer
Dengler, M. (Principal investigator)
1/01/22 → 31/12/24
Project: Research funding
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Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression.
Agrawal, D., Vizar Cisarova, K. (First author), Vosberg, S., Allmendinger, F., Munkhbaatar, E., Dandachi, N., Fernandez Hernandez, F. J., Tonietto, M., Jäger, V., Anton, M., Keller, E., Jesinghaus, M., Meinhardt, A., Haefner, V., Stoeger, T., Steiger, K., McGranahan, N., Dengler, M., Wahida, A. & Jost, P., 23 Jan 2026, In: Science Advances. 12, 4, p. eadz9227 13 p., eadz9227.Research output: Contribution to journal › Research article
2 Citations (Web of Science) -
A shift in the cellular redox state redirects aspartate for export under glucose deprivation.
Konrad, B. (First author), Blümel, G. A., Haitzmann, T., Frech, T., Vandekeere, A., Planque, M., Bubalo, V., Schindlmaier, K., Jäger, V., Dengler, M., Stryeck, S., Brcic, L., Lindenmann, J., Stiegler, P., Bresilla, D., Madreiter-Sokolowski, C., Madl, T., Eichmann, T., Kneidinger, N. & Fendt, S. & 1 others, , 3 Mar 2026, In: Cancer & metabolism. 14, 1, 20 p., 4.Research output: Contribution to journal › Research article
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Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
Höckendorf, U., Dutta, S. (First author), Kloos, A., Runtsch, M., Zötsch, C., Vosberg, S., Wang, Y., Kienreich, S., Flasch, B., Jäger, V., Stanzer, S., Prein, S., Odinius, T., Wagner, C., Buschhorn, L., Dill, V., Perfler, B., Haferlach, T., Döhner, K. & Götze, K. & 15 others, , 26 Nov 2025, In: Science Translational Medicine. 17, 826, p. eadu3313 15 p., eadu3313.Research output: Contribution to journal › Research article
1 Citation (Web of Science) -
Metabolic adaptation of glucose-deprived macrophages involves partial gluconeogenesis.
Schindlmaier, K. (First author), Haitzmann, T., Bubalo, V., Konrad, B., Jelwan, J., Blümel, G. A., Rittchen, S., Jäger, V., Dengler, M., Brcic, L., Lindenmann, J., Marsh, L., Eichmann, T., Kirchmair, A., Trajanoski, Z., Kargl, J., Muñoz-Pinedo, C. & Leithner, K., 4 Nov 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 44, p. e2419568122 10 p., e2419568122.Research output: Contribution to journal › Research article
3 Citations (Web of Science) -
CCL20 is upregulated in KRAS- driven non-small cell lung cancer via a FOXL2-NF-κB axis and displays prognostic ambivalence
Kindler, O., Moser, P., Maitz, K., Lueger, A., Runtsch, M., Achhammer, E., Santiso, A., Telebar-Zbulj, V., Zhu, X., Houghton, A. M., Jager, V., Dengler, M., Jost, P. & Kargl, J., Sept 2024, In: European Journal of Immunology. 54, p. 742-742 1 p.Research output: Contribution to journal › Conference abstract
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Signal Transduction and Targeted Therapy (Journal)
Dengler, M. (Reviewer)
2025Activity: Peer-review and editorial work › Peer-review activitiy
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Uncovering New Targets for Precision Oncology Using Innovative CRISPR Approaches
Dengler, M. (Author)
2025Activity: Talk, presentation or poster › Scientific talk or presentation › On site
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Rewiring Mitotic Cell Fate: Dual Inhibition of KIF11 and BCL-XL or MCL-1 Prevents Slippage and Efficiently Kills Lung Cancer Cells
Dengler, M. (Author)
2025Activity: Talk, presentation or poster › Scientific talk or presentation › On site
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The role of BCL-XL in cancer cell fate decision
Dengler, M. (Author)
2024Activity: Talk, presentation or poster › Scientific talk or presentation › On site
Prizes
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Walter & Eliza Hall Institute Postdoc Association International Travel Fellowship
Dengler, M. (Recipient), 2016
Prize