Projects per year
Personal profile
Career
2022 : Senior Scientist, Molecular Biology & Biochemistry, Medical University of Graz, Austria
2020 - 2022 : Postdoctoral Fellow, Molecular Biology & Biochemistry, Medical University of Graz, Austria
2014 - 2020 : PhD Candidate, Molecular Biology & Biochemistry, Medical University of Graz, Austria
2013 - 2014 : Scientific Assistant, Leibniz-Science-Institute for molecular pharmacology (FMP), Berlin, Germany
2012 - 2014 : Master’s in Biotechnology, Beuth Universität, Berlin, Germany
2011 - 2012 : Scientific Assistant, Institute of Biochemistry, Charité Campus Virchow-Klinikum (CVK), Berlin, Germany
2010 - 2011 : Scientific Assistant, Institute for Polymer Research, Helmholz Zentrum Geesthacht, Teltow, Germany
2008 - 2012 : Bachelor’s in Biotechnology, Hochschule Lausitz, Senftenberg, Germany
Research interests
- Calcium signalling
- Microscopy
- Mitochondrial ultra structure
- Super resolution microscopy
Further information
Branches of science
- 101 Mathematics
- 102 Computer Sciences
- 103 Physics, Astronomy
- 106 Biology
ÖFOS Keywords
- 106006 Biophysics
- 301114 Cell biology
- 301904 Cancer research
- 304003 Genetic engineering
- 304005 Medical biotechnology
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Projects
- 3 Finished
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MICU1 is a central switching point for signal transmission and metabolism through morphological adaptation of the cristae junction
Gottschalk, B. (Principal investigator)
1/03/24 → 31/12/25
Project: Research funding
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Adaption of the mitochondrial ultrastructure to the local micro environment in cancer cells
Gottschalk, B. (Principal investigator)
1/02/22 → 30/06/22
Project: Research funding
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MICU1 regulates mitochondrial bioenergetics by Ca2+-dependent control of the cristae junction and mitochondrial membrane potential
Gottschalk, B. (Principal investigator)
1/06/21 → 31/05/22
Project: Research funding
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MICU proteins facilitate calcium-dependent mitochondrial metabolon formation to regulate cellular energetics independently of MCU
Cohen, H. M., Gottschalk, B., Choya-Foces, C., Chatoff, A., Wilkinson, A., Berezhnaya, E., Garbincius, J. F., Johnson, A., Stevens, T. L., Howe, J. E., Lesniak, H., Schmidt, A., Ngo, J., Megill, E., Tomar, D., Snyder, N. W., Graier, W. F. & Elrod, J. W., May 2026, In: Nature Metabolism. 8, 5, p. 1106-1123 31 p.Research output: Contribution to journal › Research article
1 Citation (Web of Science) -
PAC regulates endo-, and exocytosis, and lysosomal-mitochondrial stress signaling in human mast cells.
Melek, K., Steiner, P., Kappel, S., Gottschalk, B., Andosch, A., Duggan, M., Graier, W., Zierler, S. & Peinelt, C., 20 Jan 2026, In: Cell Communication and Signaling. 24, 1, 17 p., 132.Research output: Contribution to journal › Research article
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Presenilin-1 controls glycolysis and identity of pancreatic beta cells
Koshenov, Z. (First author), Postic, S., Schoiswohl, G., van Amsterdam, S., Hois-Zelinka, V., Oflaz, F. E., Rost, R., Tiapko, O., Gottschalk, B., Hirtl, M., Bachkoenig, O. G., Koshenova, A., Erdogan, Y. C., Sagintayev, A., Krnjic, A., Pfabe, J. U., Sarikas, S., Hochreiter, B., Gindlhuber, J. & Schittmayer, M. & 10 others, , 1 Jul 2026, (E-pub ahead of print) In: Communications Biology.Research output: Contribution to journal › Research article
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Annexin A5 controls VDAC1-dependent mitochondrial Ca2+ homeostasis and determines cellular susceptibility to apoptosis.
Oflaz, F. E. (First author), Bondarenko, O., Trenker, M., Waldeck-Weiermair, M., Gottschalk, B., Bernhart, E. M., Koshenov, Z., Radulovic, S., Rost, R., Hirtl, M., Pilic, J., Karunanithi Nivedita, A., Sagintayev, A., Leitinger, G., Brachvogel, B., Summerauer, S., Shoshan-Barmatz, V., Malli, R. & Graier, W. (Last author), 16 Jun 2025, In: EMBO Journal. 44, 12, p. 3413-3447 35 p.Research output: Contribution to journal › Research article
14 Citations (Web of Science) -
A novel super-resolution STED microscopy analysis approach to observe spatial MCU and MICU1 distribution dynamics in cells.
Hirtl, M. (First author), Gottschalk, B., Bachkönig, O. A. G., Oflaz, F. E., Madreiter-Sokolowski, C., Høydal, M. & Graier, W. (Last author), Mar 2025, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1872, 3, p. 119900 11 p., 119900.Research output: Contribution to journal › Research article
4 Citations (Web of Science)
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Exploring potential TRPC1 modulators and channel activity through a TRPC1 homology model
Skerjanz, J. (Speaker), Wiedner, P. (Author), Gottschalk, B. (Author), Stockner, T. (Author), Kirchmair, J. (Author), Groschner, K. (Author) & Tiapko, O. (Author)
2023Activity: Talk, presentation or poster › Poster
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TRPC1 impact on ER calcium release mechanisms via interactions with IP3 receptors
Skerjanz, J. (Speaker), Wiedner, P. (Author), Gottschalk, B. (Author), Groschner, K. (Author) & Tiapko, O. (Author)
2023Activity: Talk, presentation or poster › Poster
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T3-induced enhancement of mitochondrial Ca2+ uptake as a boost for mitochondrial metabolism
Tawfik, I. (Author), Gottschalk, B. (Author), Bresilla, D. (Author), Graier, W. (Author) & Madreiter-Sokolowski, C. (Author)
2022Activity: Talk, presentation or poster › Poster
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Hexokinase 1 prevents mitochondrial division during energy stress
Pilic, J. (Author), Gottschalk, B. (Author), Graier, W. (Author) & Malli, R. (Author)
2021Activity: Talk, presentation or poster › Poster
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Investigating the stress sensitivity of the secretory pathway in cancer cells using high-resolution fluorescence imaging
Rauter, T. (Author), Gottschalk, B. (Author), Burgstaller, S. (Author), Ramadani-Muja, J. (Author), Bischof, H. (Author), Hay, J. (Author), Graier, W. (Author) & Malli, R. (Author)
2021Activity: Talk, presentation or poster › Scientific talk or presentation › On site
Prizes
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Preis der Max-Buchner-Forschungsstiftung für technische Chemie an Hochschulen
Gottschalk, B. (Recipient), 2015
Prize