Systematische Erhebung von Hämatochezie im Kindes- und Jugendalter mit besonderem Augenmerk auf Antibiotika-assoziierte hämorrhagische Kolitis und den enteralen Pathobionten Klebsiella oxytoca

Abstract

Objectives and Study: Hematochezia in children and adolescents is a troubling sign for parents as well as for physicians. The spectrum of underlying diseases is diverse and ranges from benign to potentially life-threatening. Systematic pediatric data on the causes of hematochezia are scarce. This prospective study aimed at elucidating the range of disorders causing hematochezia in children. A second aim of this study was to investigate antibiotic-associated colitis (AAC) presenting with hematochezia, focusing on antibiotic-associated hemorrhagic colitis (AAHC), a recently described entity caused by Klebsiella (K.) oxytoca. Currently the preconditions, incidence and age pattern of AAHC in children and adolescents are unclear. Methods: Infants, children and adolescents with visible bloody stool were prospectively recruited at 5 different Austrian pediatric hospitals between May 2011 and December 2012. Patients were grouped in infants (

Datum der Bewilligung	2015
Originalsprache	Deutsch (Österreich)
Gradverleihende Hochschule	Medizinische Universität Graz
Betreuer/-in	Karl Martin Hoffmann (Betreuer*in) & Christoph Hoegenauer (Mitbetreuer*in)