Evaluation of vitamin D and bone markers in patients with hepatitis B infection with and without tenofovir treatment

Abstract

Background: Increased bone turnover rates as well as vitamin D deficiency and insufficiency have been observed in HIV-infected individuals receiving tenofovir disoproxil fumarate (TDF). There is a lack of data regarding the effects of TDF use on bone markers and vitamin D in HBV-infected individuals. Objectives: The aim of the present pilot study was to evaluate bone markers and vitamin D levels in HBV-infected patients with and without TDF therapy. Material and methods: A total of 41 HBV-infected patients attending the Division of Gastroenterology and Hepatology at the Medical University of Graz were enrolled including 23/41 patients with a serum HBV DNA level of ≥2000 IU/ml eligible for antiviral treatment (TDF Group) and 18/41 patients with a serum HBV DNA level of

Datum der Bewilligung	2016
Originalsprache	Englisch
Gradverleihende Hochschule	Medizinische Universität Graz
Betreuer/-in	Harald Kessler (Betreuer*in)