CHARACTERISATION OF RETROGRADE BLOOD-FLOW IN THE MAIN PULMONARY ARTERY IN PATIENTS WITH ELEVATED MEAN PULMONARY ARTERIAL PRESSURE THROUGH CARDIAC MAGNETIC RESONANCE PHASE-CONTRAST IMAGING A RETROSPECTIVE STUDY

Abstract

Pulmonary hypertension (PH) is a life-threatening disease, which is characterised by an elevation of the mean pulmonary artery pressure (mPAP) at rest ≥25mmHg. According to current guidelines, PH is diagnosed by right heart catheterisation (RHC). Magnetic resonance phase-contrast imaging (MR-PCI) enables to estimate elevated mPAP with physical accuracy by the assessment of the persistence of a characteristic blood flow vortex in the main pulmonary artery (MPA). This vortex causes a retrograde flow whose onset time (“retrograde flow onset time”, ROT) in the cardiac interval can be used as a non-invasive index to diagnose pulmonary arterial hypertension (PAH). The purpose of this study was to investigate if this method can be employed for the diagnosis of PH in general. In the present study 108 patients (n=54 with mPAP≥25mmHg / n=54 with mPAP

Datum der Bewilligung	2015
Originalsprache	Englisch
Gradverleihende Hochschule	Medizinische Universität Graz
Betreuer/-in	Ursula Reiter (Betreuer*in) & Michael Fuchsjäger (Mitbetreuer*in)